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Edna S. Kaneshiro |
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| Address: Edna Kaneshiro Department of Biological Sciences, ML006 University of Cincinnati Cincinnati, Ohio 45221-0006 |
Telephone: (513) 556-9712 FAX: (513) 556-5280 Email: Edna.Kaneshiro@UC.Edu
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The primary contributions from this lab have been on the lipids of eukaryotic protists, including freeliving, parasitic, and opportunistic pathogens. Although work on a number of different protozoa are being performed, our current focus is on the AIDS-associated opportunistic infection caused by Pneumocystis carinii. This organism causes a type of pneumonia that can lead to the death of immunocompromised individuals. Pneumocystis proliferates extracellularly in the lung alveolus where lipids constitute a major part of lung surfactant. Thus, lipids are thought to be important to the nutrition, physiology and metabolism of the organism. The biosynthesis of pathogen-specific lipids represent potential targets for drug development. We also have an interest in the cell biology and life history of this poorly understood opportunistic infectious agent.
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